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Initiate the dosing regimen for each patient individually, taking into account the patients underlying cause and severity of pain, prior analgesic treatment and response, and risk factors for addiction, abuse, and misuse [see WARNINGS]

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It is important to note that while bloating can be uncomfortable and may affect quality of life, it is generally considered a manageable side effect rather than a serious safety concern

An agonist is a molecule that binds to a receptor and activates it, producing a biological response

At 5mg: The first dose where GI effects become noticeable for many patients

mains lead with dense, whole-food protein (chicken, beef, salmon, eggs), so even a half portion moves you toward preserving muscle