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For example, hypoxia has been shown to induce a stem-like phenotype through HIF-mediated transcriptional reprogramming, 119 whereas inflammation and therapy-induced stress can promote dedifferentiation of non-CSCs into CSC-like cells

Front Psych 13:813304 Sharifi-Rad M et al (2020) Lifestyle, oxidative stress, and antioxidants: back and forth in the pathophysiology of chronic diseases

At the same time, increased levels of inflammatory molecules, such as LPS from harmful bacteria, can lead to systemic-wide inflammation (Obrenovich et al., 2020)

Avoid repeated freeze-thaw cycles each thermal cycle causes progressive peptide degradation

Flaherty S, Strauch P, Maktabi M, Pybus BS, Reichard G, Walker LA, et al

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