The ability to shuttle between the +1, +2, and +3 oxidation states is responsible for the versatile chemistry of vitamin B 12 , allowing it to serve as a donor of deoxyadenosyl radical (radical alkyl source) and as a methyl cation equivalent (electrophilic alkyl source)
This vitamin has an important role in the production of important neurotransmitters (serotonin and dopamine)
2021. NNMT inhibition reduces obesity and diabetes risk
In addition, B12 deficiency-associated fatigue is often accompanied by other symptoms such as numbness and tingling, cognitive impairment (memory and concentration problems), mood swings (depression), skin changes (pale skin), shortness of breath, or fast heart rate
5-Amino-1MQ alone improved grip strength to a greater degree than rigorous exercise training alone, and combined treatment produced sustained increases in daily running distance that did not taper off in the way exercise-alone groups did, suggesting reduced post-exercise muscle recovery requirement
People who have conditions that make absorption difficult are also good candidates for B12 shots
