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However, both agencies concluded that the currently available evidence does not support a causal relationship between GLP-1 drugs and suicidal thoughts or actions (9,10)

Take home message Weight-loss injections are designed as additional tools for weight management interventions and shouldnt be considered lifelong medications

Functional bitter taste receptors are expressed in brain cells

239,240 In summary, GLP-1 lowers blood glucose levels and inhibits glucagon secretion through direct action on -cells, promotion of insulin secretion, and regulation of gastrointestinal activity

Gut hormones help to control hunger and satiety

Dehydration and kidney function Persistent vomiting or diarrhoea can lead to dehydration, which may in turn affect kidney function