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The reduction by dutasteride of prostate cancer events (REDUCE) trial is another multicenter, randomized, international, placebocontrolled, double blind clinical trial initiated in 2003 to evaluate the ability of dutasteride to decrease the risk of biopsy detectable prostate cancer in men with moderately elevated PSA levels

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When both nutrients are deficient, B12 should be initiated before or alongside folate to avoid worsening neurological symptoms