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Asimismo, algunos se asociaban con potenciales efectos indeseables, como el riesgo de insuficiencia cardiaca o de fracturas (complicaciones especialmente prevalentes per se en pacientes con ERC), como las tiazolidindionas, o el aumento de peso o riesgo de hipoglucemia con sulfonilureas e insulina

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It could also be expected to increase compliance with adjunctive treatments such as behavioral and motivational therapy. Le Roux said the findings need to be validated through randomized controlled trials, especially a trial enrolling adults with alcohol use disorder

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