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With 10.1 crore people living with abnormal blood sugar levels, India is already regarded as the diabetes capital of the world

Through the analysis of these binding interactions and dynamic behaviors, we intend to identify residues that significantly enhance affinity, assess reliable binding modes, and offer essential insights for the development of effective hTYR inhibitors

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Then, 15 g of protein was mixed with NativePAGE sample buffer (Invitrogen), Coomassie G-250 and protease inhibitor, loaded into the lanes of a 312% Bis-Tris NativePAGE gel (Invitrogen) and run according to the manufacturers instructions

Revised May 2024, modified May 2025