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Y., He, Q

Ann Intern Med 123 : 747753

The FDA labels for these pills explicitly note this concern

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THC-induced hyperphagia (the munchies) can bypass the satiety signals sent by the GLP-1 medication

Pre-Research Assessment: Complete medical history and physical review Baseline blood glucose and HbA1c Liver function tests (ALT, AST, bilirubin) Renal function tests (creatinine, BUN, eGFR) Complete blood count Lipid panel IGF-1 and IGFBP-3 levels Thyroid function tests Screening for contraindications During Research Tracking: Regular blood glucose tracking (frequency based on dose and risk factors) Periodic assessment of liver and renal function Tracking for signs of fluid retention Assessment of injection sites Records of any adverse findings Regular evaluation of research parameters Post-Research Assessment: Repeat baseline laboratory tests Evaluation of any persistent effects Assessment of research outcomes Planning of appropriate follow-up Managing Adverse Observations Research protocols should include plans for managing possible adverse findings