Studies have shown that a healthy GM correlates with high microbial diversity and abundance (124128), which is largely influenced by the host's diet, lifestyle, and genetic predisposition
Impaired GPX4 activity elicits ferroptosis in alveolar type II cells promoting PHMG-induced pulmonary fibrosis development
doi: 10.1038/s41577-020-00478-8 158 MajTWangWCrespoJZhangHWangWWeiSet al
In the realm of natural compounds, ellagic acid alleviates glucosamine-sulfate-induced ulcerative colitis in mice by modulating gut microbiota and inhibiting ferroptosis [304]
PMID 11375228
Signal transducer and activator of transcription 3 (STAT3), a crucial cytoplasmic transcription factor in the STAT family, consists of 770 amino acids and possesses a complex domain structure, facilitating its diverse roles in cell signaling and gene regulation (Ma et al., 2020)