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10.1016/j.jcmgh.2022.02.009 37 JahnB.ArvandiM.RochauU.FieglH.GoebelG.MarthC.et al (2017)

Type 2 diabetes mellitus-associated cognitive dysfunction: advances in potential mechanisms and therapies

80.Foley E, Marsh C

The methyl donor for this reaction is S-adenosylmethionine (SAM or AdoMet) and the reaction is catalyzed by the enzyme guanidinoacetate N -methyltransferase

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The liver processes nutrients absorbed from the gut, and the gut relies on the liver for bile and detoxification support