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Therefore, persistent interactions with misfolded or metastable proteins can overload the chaperone system, thereby ultimately compromising global protein homeostasis

When co-treated with Fer1, the PI uptake was effectively suppressed in the RSL3-treated 3D PTC spheroids, further reinforcing our previous findings of cytoprotective effects and ferroptosis pathway abrogation by Fer1 in RSL3-treated PTC cells in 2D

For best results, consider scheduling regular injections as part of your wellness routine

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