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Efficacy and Safety of OnceWeekly Semaglutide Versus Once-Daily Insulin Glargine as Add On to Metformin (with or without Sulfonylureas) in Insulin-Naive Patients with Type 2 Diabetes (SUSTAIN 4): A Randomised, OpenLabel, Parallel-Group, Multicentre, Multinational, Phase 3a Trial

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GLP-1 Clinical Trials Show Promising Reduction in Body Weight The most cited GLP-1 study is the STEP 1 trial , which evaluated semaglutide, the active ingredient in Wegovy, in non-diabetic adults with obesity