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Naturally occurring amylin is co-secreted with insulin by pancreatic beta cells to assist in glycemic regulation and satiety, but its brief biological half-life limits its utility in long-term laboratory models

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From a safety perspective, SC administration of apomorphine may cause injection site reactions such as bruising (16%), granulomas (4%) or itching (2%), but these typically do not lead to discontinuation ( 5% of patients) [9]

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It alters metabolic thermogenesis and promotes synaptogenesis via hepatocyte growth factor signaling