This reaction, known as the Herxheimer reaction or SIBO die-off, can be confusing and distressing if youre not prepared
In 2022, more than 5 million prescriptions for Ozempic, Mounjaro (tirzepatide), Rybelsus (semaglutide) or Wegovy were written for weight management, compared with just over 230,000 in 2019a 2,082% increase, according to data from Komodo Health
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Below is a general timeline based on common clinical experience and published research, with the reminder that individual responses vary
Overweight was defined in the study as having a body mass index of 25 or above