is it safe to take semaglutide while pregnant GLP-1 Pregnancy Safety: What You Must Know Semaglutide and Pregnancy | Eternity

Green Tea Extract at the levels used in supplements has a generally favorable safety profile in healthy adults, though high-dose Green Tea Extract has been associated with rare cases of liver stress in susceptible individuals -- a concern at doses significantly higher than what is typically found in supplement formulations

the FDA advisory committee then voted against permitting their compounding, leaving them restricted (source)

A patch test before full application can identify potential sensitivities

Macimorelin (Macrilen) gained FDA approval in 2017 as a diagnostic agent for adult GH deficiency, validating the oral GHS-R1a mechanism for at least acute GH stimulation testing 15

Assuming you followed the above advice and used an appropriate binding buffer and your protein isnt huge, then a likely reason for this is that the expression yield is much lower than you expected

Figure 7 Discussion Diverse metabolomic alterations are reported in the acute phase of SARS-CoV-2 infection (42, 43)