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Economic Impact and Access Challenges The financial burden of GLP-1 medications remains substantial, with average prescription costs exceeding $1,500 ^26

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Instead of relying primarily on historical relationships, many sponsors are exploring more data-driven approaches to site selection, including: regional disease heatmaps investigator performance analytics patient population modeling AI-assisted feasibility analysis These approaches aim to answer a fundamental question: Which sites can actually recruit the patients required for modern metabolic trials

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