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As a transcriptional suppressor, Hes1 in the retina inhibits the differentiation of specific cell types and leads to excessive gliosis, increased inflammatory cytokine release, and ECM imbalance

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animals without a gut microbiome) exposed to maternal separation do not show changes in anxiety-like and depression-like behavior [68]

doi: 10.3382/ps/pew041 32 EsmaeiliV.ShahverdiA

Prince M, Wimo A, Guerchet M, Ali GC, YuTzu W, Prina M (2015) The global impact of dementia: an analysis of prevalence, incidence, cost and trends

This sudden stretch causes tiny tears inside the dermis, breaking the collagen and elastin fibers and forming lines on the surface