The limitation is penetration
Proc Natl Acad Sci USA 93: 1442814433
Third-party tested for purity and identity where applicable
The GGT is the only enzyme that can initiate catabolism of GSH and GSH-adducts (e.g., GSSG, glutathione S -conjugates, and glutathione complexes)
Research Applications & Usage Information Redox Homeostasis and Oxidative Stress Models : Studies how shifts in GSH/GSSG affect ROS handling, stress signaling, and oxidative damage markers
Depending on stimuli, microglia can adopt distinct phenotypes: the M1 pro-inflammatory state (induced by lipopolysaccharide and characterized by production of cytokines such as TNF-, IL-1, and IL-6) and the M2 anti-inflammatory state (induced by IL-4 or IL-13, promoting repair) [122, 123]