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It plays a crucial role in protecting cells from damage, supporting the immune system, and promoting detoxification

Purification and characterization of a novel brain-specific 14-kDa protein

Sensing this, the heart pauses, its electrical signals reset, and then it resumes beating

& Treisman, R

[DOI] [PubMed] [Google Scholar] 88.Repsold L, Joubert AM

Similar strategies may also be used to deplete IgA, as explored with the pre-clinical candidate BHV-1400 [434], which leverages ASGPR biology in a manner similar to BHV-1300 and could represent an alternative to the likely mechanism-of-action of ARGX-121, and to deplete IgE, as shown with lysosomal targeting chimeras coupling pH-sensitive target binding and ASGPR-mediated endolysosomal delivery to FcRn-mediated cellular transport of the potential therapeutic molecule [435]