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The peptide's natural occurrence in the body, well-established safety profile from decades of topical use and clinical research, and remarkable breadth of beneficial biological effects make it a compelling example of a naturally derived regenerative peptide with both proven cosmetic applications and ongoing exploration of broader therapeutic potential

Rossignoli G, Krmer K, Lugar E et al (2021) Aromatic l -amino acid decarboxylase deficiency: a patient-derived neuronal model for precision therapies

What panel members said on the record, though, turned less on the evidence base than on safety specifically

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Acetyl-CoA is a necessary intermediate for the synthesis of lipids, and without it, cancer cells are not viable