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162 These inflammatory cytokines reduce the expression of NAMPT

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Carnitine has been shown to be an endogenous substance with anti-inflammatory properties [47], as it inhibits the activity of NF-B and other core transcription factors involved in the inflammatory response and effectively reduces the levels of proinflammatory cytokines (e.g., IL-1, IL-6, and TNF-) [48, 49]