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Clin Exp Immunol 180:4051

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Remarkably, in a trial using high-dose thiamine for fatigue related to inflammatory bowel disease (IBD), the relative abundances of Faecalibacterium prausnitzii , a member of the Ruminococcacea family, and Roseburia hominis , a member of the Lachnospiraceae family, inversely correlate with fatigue severity both pre- and post-treatment with thiamine (62)

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This is reasonable practice, especially if you have any cuts or abrasions on your hands

Very easy to administer, instructions are great and it works