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Since slow-acting cell death processes can proceed following ototoxin removal (Owens et al., 2009), we next asked if Dihexa-mediated protection was still present 6 h after neomycin exposure

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6 Challenges of unmodified aptamer in immunotherapy application Although aptamers hold significant promise, most have failed to achieve the required safety and efficacy benchmarks in human clinical trials

doi: 10.1038/nature19094 221 De SordiLLourenoMDebarbieuxL

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Choosing the Right Peptide The following table highlights how the specific mechanisms and research of each peptide impact the clinical choice