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Evidence Supporting Exercise and Protein Intake There are currently no clinical trials specifically examining protein intake during GLP-1 treatment, but higher protein intake combined with resistance training is beneficial: A 2025 case series published in SAGE Open Medicine described three patients using semaglutide or tirzepatide who engaged in resistance training 3 to 5 days weekly and consumed protein at 0.36 to 0.77 g/lb of total body weight (0.73 to 1.04 g/lb of fat-free mass)
[DOI] [PubMed] [Google Scholar] 17.Sikiric P, Separovic J, Buljat G, et al
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Protein Protein has long been associated with feeling fuller after meals, and GLP-1 helps explain why
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Haderlie SA, Hieber JK, Boles JA, Berardinelli JG, Thomson JM
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