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iWAT, inguinal white adipocyte tissue

Front Immunol 15:1332317 Cheng D, Zinker BA, Luo Y et al (2022) MGAT2 inhibitor decreases liver fibrosis and inflammation in murine NASH models and reduces body weight in human adults with obesity

Side effects sometimes necessitate discontinuation

benefit was preserved in the prespecified subgroup receiving sodium-glucose cotransporter-2 inhibitors (SGLT2i) at baseline, which supports combined GLP-1RA + SGLT2i use as a supported option pursuing complementary pathways [4], [33]

Designed for both overhead and underground tanks, it helps prevent water overflow and dry-run pump damage

But if the device proves safe and comes with fewer side effects than existing options, some see an opportunity for it to address one of the biggest challenges in obesity treatment: helping patients stay on therapy and maintain their weight loss over time