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Why Wegovy isnt recommended during pregnancy The main concern comes down to how medication affects both maternal nutrition and fetal development

Proper nutrition while on a GLP-1 supports stable blood sugar, energy levels, and muscle health, even during weight loss

PMID: 34860904

It can be taken at any time of the day, with or without food and without water restrictions

However, FAERS has well-known limitations: Reports are spontaneous and incomplete Reporting stimulated by media attention and warnings No denominator (unknown number of exposed users) Thyroid cancer not subtype-adjudicated Confirmation bias (clinicians primed to connect drug and outcome) FAERS can answer: "Is this being reported more?" It cannot answer: "Does this drug cause thyroid cancer?" Appropriate Use of FAERS: FAERS findings are hypothesis-generating signals requiring controlled observational worknot evidence of causality

In line, TGR5 and FXR agonists have shown promising results in the treatment of metabolic and inflammatory diseases, such as IBD and T2D (37)