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Other studies have confirmed that NRF2, speedy/RINGO cell cycle regulator family member A (SPY1), and myeloperoxidase (MPO) regulate ferroptosis and lipid peroxidation in motor neurons, thereby modulating neural function

They signal fibroblasts to make more collagen and elastin

As superoxide is subject to efficient dismutation by cellular superoxide dismutases, it is possible that NFT might directly interact with Keap1 to induce the observed release of Nrf2 and its escape from proteasomal degradation

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Moreover, folic acid, the synthetic form of folate, effectively scavenges oxidizing free radicals and inhibits lipid peroxidation [115]

Glutathiones major role is in fighting oxidative stress, a naturally occurring process in cells as a byproduct of metabolism