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Age, gastrointestinal disorders, and certain medications can also interfere with B12 absorption

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Some chemotherapy drugs or antiretroviral medications (for HIV) that suppress bone marrow might also blunt the effectiveness of B therapy

If you experience severe pain, signs of infection (redness, warmth, swelling), or an allergic reaction (rash, itching, difficulty breathing), seek medical attention immediately

This may be because the ability to absorb vitamin B12 effectively Other factors Risk factors for having a vitamin B12 deficiency may include: high alcohol intake AIDS some inherited conditions How much vitamin B12 do I need

Allow the injection site to dry completely before administering the shot