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Key Finding: At the 12mg dose, 100% of participants lost at least 5% body weight, 93% lost at least 10%, and 63% lost at least 20% of their starting weight
Several dose escalation arms were studied, with doses ranging from 1 mg up to 12 mg once weekly
Not only are they increasingly being prescribed for the treatment of Type II diabetes, but they have also recently gained a lot of popularity in the world of obesity treatment and long-term weight management
Usage disclaimer: A subjects dosage and administration should be determined by a qualified healthcare professional
In the STEP-1 trial published in The New England Journal of Medicine in 2021, once-weekly subcutaneous semaglutide at 2.4 mg produced a mean placebo-adjusted body weight reduction of 12.4% at 68 weeks in adults with overweight or obesity (Wilding et al., NEJM, 2021)