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If gastrointestinal disturbance persists or becomes severe, discontinuation and consultation with a healthcare professional is advised

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Additionally, it switches melanin production from dark eumelanin to lighter pheomelanin, theoretically resulting in brighter skin

A summary score is generated by multiplying individual scores for severity (range 19) and frequency (range 18) for each item and adding these up

doi: 10.1038/s41574-022-00683-6 7 PofiRCarattiGRayDWTomlinsonJW