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10.1016/S0140-6736(15)00055-0 19 CollinsS

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The caffeine can speed up your heart rate, so Birks says that if you have a heart condition, you should check with your doctor before drinking it

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Granuloma Inguinale Calymmatobacterium granulomatis, a Gram-negative bacterium, is the causative agent of granuloma inguinale or donovanosis (34,41)