E.GlauserT
Mechanism of Action: GHK-Cu promotes tissue repair and regeneration by influencing gene expression related to tissue remodeling, collagen synthesis, and angiogenesis (new blood vessel formation)
The bulks list is the relevant lever for peptides, almost none of which are FDA-approved drugs in their compounded forms
Compatible with: Hyaluronic acid (for hydration) Niacinamide (for barrier support and tone) Growth factors Peptides (like Matrixyl or Argireline) Use with caution: Vitamin C (especially L-ascorbic acid) may destabilize copper peptides if mixed directly Retinoids can cause irritation when layered with GHK-Cu unless used at separate times (e.g., retinoid at night, GHK-Cu in the morning) AHAs and BHAs can lower skin pH and potentially reduce the effectiveness of copper peptides Spacing out these ingredients or consulting with a provider for a personalized routine can maximize benefits and avoid conflicts
When S is low, 1-1.4, the GS flux rises more rapidly than the GPX flux, pushing GSH up
For example, FGF studies in 1990s (Damien et al., 1993