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Authors have tried to differentiate women with lipedema from those with Dercum disease by examining populations and finding that people with Dercum disease tend to have other pain disorders including higher pain scores, fibromyalgia, abdominal pain, and migraines, and more often have lipomas, cognitive dysfunction and shortness of breath

Studies of Sermorelin have investigated its ability to improve these parameters

2018;96(3):e269-e276

Notably, gene-expression studies have associated GHK-Cu with the modulation of thousands of genes tied to tissue remodeling and the inflammatory response, which is why it is studied as a foundational signal peptide in repair models

doi: 10.4049/jimmunol.1202388 86 YangCAHuangSTChiangBL

Science 349:10711075 Kataya AMR, Reumann S (2010) Arabidopsis glutathione reductase 1 is dually targeted to peroxisomes and the cytosol