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3: 5860 Arienti G, Ramacci MT, Maccari F, et al

Each medications effectiveness can vary, but head-to-head data suggest that tirzepatide may be the most effective GLP-1 for weight loss to date

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"We wanted to make sure that we stayed on message: This was a temporary thing and the goal is to taper off the drugs and [not to] stay on GLP-1s permanently," says a former Calibrate health coach, who worked with several hundred of the company's customers during her time at the company, but asked for anonymity in order to discuss her former employer