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The Phase 3 TRIUMPH program will determine whether, and at what doses, retatrutide reaches the market

In the SURMOUNT-1 trial, 95 percent of participants taking tirzepatide reverted to normal blood sugar over 176 weeks, and 99 percent stayed diabetes-free

It's also common to lose some muscle mass along with fat while on these drugs, which can be problematic, Kessler writes

This is especially useful for clinics, weight loss programs, and patients who need customized care

In clinical trials, people taking this drug saw significant weight loss

Lab Testing: What Gets Measured and Why It Matters Not everyone is required to do labs, but if your provider flags potential risks like elevated blood sugar or liver concerns, they may ask you to get blood work done before starting