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On the other hand, the inhibitory activity of butyrate toward histone deacetylases (HDAC) has also been extensively described in literature due to HDAC involvement in transcriptional regulation, metabolism, metastasis, oncogenesis, and ischemic brain events (80, 81)

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Functions of the brain mitochondria in physiological conditions The human brain, which weight accounts for ~2% of the body weight, consumes 20% of the whole bodys oxygen

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