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Other than this limited number of patients, the consequences of extended and repeated use of dihydroergotamine mesylate nasal spray on the nasal and/or respiratory mucosa have not been systematically evaluated in patients

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However, ongoing research, such as the FLOW trial, which had been comparing GLP-1RAs to a placebo in patients with T2D and CKD, was recently halted prematurely due to their effectiveness

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