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Recently the dual agonist of GLP-1RA/glucose-dependent insulinotropic polypeptide (GIP) (Tirzepatide) has been found to improve glycaemic control and reduce weight in patients with T2D and severe obesity [12] and in patients with severe obesity to reduce weight by up to 20% after a 72 week study period [13]

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Van Haren R, Rajaram R, Correa A, Sepesi B, d R, Hofstetter W, Roth J, Swisher SG , Walsh G, Vaporciyan A, Mehran R, Antonoff M

Imaging studies are necessary to reach the diagnosis and include, from time to time, abdominal ultrasound, CT scan, ERCP, MRCP, and percutaneous transhepatic cholangiography