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Reproductive Toxicity of Rhizoma Sparganii ( Sparganium Stoloniferum Buch.-Ham.) in Mice: Mechanisms of Anti-angiogenesis and Anti-estrogen Pharmacologic Activities

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This effect is achieved through the activation of signaling pathways such as the ERK1/2, PI3K/AKT, and cAMP/PKA/-cat-Ser675 pathways, which are mediated by GLP-1RAs

That is a 99.7% animal-to-human ratio

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