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Anabolic steroids activate receptors throughout the body, causing systemic effects: liver toxicity, cardiovascular strain, hormonal shutdown, acne, hair loss

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However, combining two appetite-suppressing agents intensifies the risk of side effects including nausea, constipation, fatigue, and reduced caloric intake below safe minimums

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These medications are thought to improve insulin sensitivity and reduce hepatic glucose production, which may indirectly affect lipid metabolism