Nov 2008;116(10):600-605
received funding via subcontract under National Institutes of Health (R01 DK128443) to R.P.D., M.R.H
The most frequently reported side effects during retatrutide initiation are gastrointestinal, including nausea, vomiting, diarrhoea, and abdominal discomfort
Detection of oncogene amplifications in medulloblastomas by comparative genomic hybridization and array-based comparative genomic hybridization
Jiahui and colleagues reported that a DNAJC subfamily member, T-cell activation inhibitor in mitochondria (TCAIM), provides posttranslational modification and protection to -ketoglutarate dehydrogenase in an HSPA9-dependent manner (Jiahui et al., 2025), revealing a novel mode of mitochondrial chaperoning
Both medications are very effective at controlling blood sugar levels and aiding in weight loss, with retatrutide showing a small advantage in trials, but tirzepatide has more long-term data as its already been FDA-approved