Systemic augmentation and other indications: Evidence that supplementation reliably increases systemic GSH is not robust
In HT, the thyroid gland is gradually destroyed resulting in reduced production of thyroid hormones and triggering symptoms that include fatigue, weight gain, constipation, increased sensitivity to cold, dry skin, depression, muscle aches and reduced exercise tolerance ( 5 )
Excessive reactive oxygen species directly attack endothelial cell membranes, proteins, and DNA, leading to cellular dysfunction and death (45, 46)
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Furthermore, in both the plasma (Figure 3C) and liver (Figure 3D) there was a 50% decrease in GSH levels following all of the CS exposure times