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doi: 10.4143/crt.2015.310 88 RogerPPvan StaverenWCCoulonvalKDumontJEMaenhautC

Fatigue is sometimes reported during the first two weeks at this dose, though it is difficult to determine whether this is a direct effect of the medication or a consequence of significantly reduced caloric intake

How AI Doctor Consultations Work Intake and Symptom Assessment The first step in an AI-based consultation is an intake, where the system asks structured questions about symptoms, duration, past medical history, medications, and any relevant lifestyle factors

So that, to me, is pretty strong evidence

Wadhwa K, Pahwa R, Kumar M, Kumar S, Sharma PC, Singh G, Verma R, Mittal V, Singh I, Kaushik D, Jeandet P (2022) Mechanistic insights into the pharmacological significance of silymarin

For instance, poor sleep might lead to increased inflammation, which in turn accelerates NAD+ depletion