tirzepatide vs semaglutide benefits caused roughly half as many patients to stop treatment because of gastrointestinal side effects as semaglutide. In the first major head-to-head obesity trial, GI side effects caused treatment discontinuation in: Tirzepatide Tirzepatide vs Semaglutide: Which Weight

Kanbay M, Copur S, Siriopol D, Yildiz AB, Gaipov A, van Raalte DH, et al

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Overall, many patients in both groups explored other weight-management treatment options within 12 months of stopping their initial GLP-1 injectable: Researchers say the findings underscore the importance of personalized, ongoing support for patients seeking obesity treatment even when they stop medication

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