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9 The semaglutide group exhibited significant improvements in symptoms and physical limitations, assessed using the Kansas City Cardiomyopathy Questionnaire Clinical Summary Score (KCCQ-CSS), with the change in KCCQ-CSS being the primary trial endpoint

It is a synthetic version of the hormone insulin-like growth factor 1, which is an anabolic hormone that is naturally found in the human body, and its levels depend on the production of growth hormone

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However, the leading theory behind PD pathogenesis is the accumulation of alpha-synuclein aggregates within cells, which trigger neuroinflammation and neuronal apoptosis (Kim et al., 2019)