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Sedlak TW, Saleh M, Higginson DS, Paul BD, Juluri KR, Snyder SH
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GHK-Cu, o glicil-L-histidil-L-lisina-cobre, fue identificado por primera vez en 1973 por el bioqumico Dr
It activates antioxidant enzymes such as superoxide dismutase (SOD), promotes collagen and elastin synthesis, and suppresses fibrotic pathways by inhibiting TGF-?1 signaling
In contrast, NAC-S2 treatment did not affect adjacent signaling pathways, as evidenced by irregular phosphorylation of mitogen-activated protein kinase (MAPK), c-Jun N-terminal kinase (JNK), and extracellular signal-regulated kinase (ERK)
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