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While these data are overall re-assuring on the effectiveness of oral semaglutide in clinical practice, there is still a lack of long-term studies and continuous post-marketing monitoring is warranted

Studies conducted on the activity of enzymes have shown that patients are characterized by lower GR activity

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Treatment should be discontinued if weight loss is less than 5% after 12 weeks on the full 3.0 mg daily dose

doi:10.1016/0300-483x(81)90067-6