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IU1 series exhibit high selectivity as inhibitors of human USP14, and optimal exposure of functionalizing elements when bound in the allosteric pocket of USP14 20 (Fig

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Abstract Researchers have implicated mercury (Hg) exposure in the pathogenesis of autism spectrum disorder (ASD) through multiple mechanisms, including oxidative stress, mitochondrial dysfunction, and glutamatergic dysregulation

Recently, ALA has drawn significant attention for its potential benefits in easing diabetic neuropathy symptoms and improving metabolic health