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Finding that interesting loop later led to our understanding of the sensing mechanism, Birsoy says
It peaks in the first 24 to 48 hours after each injection and typically diminishes significantly after the first several weeks of treatment
doi: 10.1016/j.physbeh.2013.07.009 5 BlomainESDirhanDAValentinoMAKimGWWaldmanSA
That matters because muscle is metabolically active tissue
Hospitals must update: Pre-operative medication history form (add GLP-1 section), anaesthetic protocol (RSI for all GLP-1 patients), post-operative monitoring protocol (aspiration risk), and nursing education (GLP-1 patients require enhanced post-op monitoring)
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