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BCKAs can be metabolized by BCKDH to branched-chain acyl-CoA, and blocking this step causes serious metabolic disorders, such as maple syrup urine disease (Xu et al., 2020) and propionic academia (Chen et al., 2017)

More recent data explores gene expression modulation, with analysis suggesting GHK-Cu influences a broad network of biological pathways tied to tissue integrity and cellular repair

Side effects are rare and generally mild, with the most common being slight scalp irritation or redness

If you have severe or prolonged side effects, such as redness, irritation, peeling, flaking, and dryness, contact your clinician for guidance

The link is (surprise!) mitochondria